⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041147 | 0.65 | — | — | |
| SCHEMBL2494921 | 0.62 | — | — | |
| SCHEMBL2497765 | 0.62 | — | — | |
| SCHEMBL2043265 | 0.60 | — | — | |
| SCHEMBL2044398 | 0.60 | — | — | |
| SCHEMBL1033358 | 0.60 | — | — | |
| SCHEMBL212845 | 0.56 | CYP19A1 (0.81) | — | |
| SCHEMBL9789472 | 0.54 | CYP19A1 (0.77) | — | |
| SCHEMBL16541066 | 0.54 | CYP19A1 (0.77) | — | |
| SCHEMBL9789477 | 0.54 | CYP19A1 (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062879-A | 8-AZOLYLMETHYLQUINOLINES AND HERBICIDAL USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-05 | — | — | US | claimed |
| US-20120291159-A1 | Azoline Compounds for Combating Invertebrate Pests | BASF SE (DE) | 2012-11-15 | — | — | US | disclosed |
| WO-2011073444-A2 | AZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2011-06-23 | — | — | WO | disclosed |
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| CN-1105720-C | Imidazopyridazines compound | AOTANNA MEDICINE AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| EP-0706523-B1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-01-24 | — | — | EP | disclosed |
| US-6162809-A | Pyridylthio compounds for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-19 | — | — | US | disclosed |
| US-6107312-A | BACTERICIDE | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-22 | — | — | US | disclosed |
| US-6043242-A | TREATING A MAMMAL AFFLICTED WITH A DISEASE BASED ON HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-28 | — | — | US | disclosed |
| CN-1246120-A | Imidazopyridazines compound | BYK GULDEN LOMBERG CHEM FAB (DE) | 2000-03-01 | — | — | CN | disclosed |
| WO-1996002505-A1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |
| WO-1995034554-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995001351-A1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-01-12 | — | — | WO | disclosed |
| US-5246914-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |
| EP-0527378-A1 | Salicyl(thio)ethers derivatives, process and intermediates for their preparation | BASF Aktiengesellschaft (DE) | 1993-02-17 | — | — | EP | disclosed |
| US-5013742-A | Analgesics, Anesthetics, Narcotic Antagonists | BOC, INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4957929-A | ANALGESICS, ANESTHETICS | BOC, INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4921864-A | 4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds | BOC, INC. (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0315405-A1 | 4-phenyl-4-(N-(2-fluorophenyl)amido) piperidine derivatives | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4791121-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1988-12-13 | — | — | US | disclosed |