SCHEMBL1033358

SCHEMBL1033358

O=[N+]([O-])C1=CC=C[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532014 0.70 CYP19A1 (0.30)
SCHEMBL448999 0.62
SCHEMBL2041806 0.60
SCHEMBL2037405 0.60
SCHEMBL919986 0.56
SCHEMBL14392214 0.56 LMNA (0.33)
SCHEMBL212845 0.56 CYP19A1 (0.81)
SCHEMBL16541066 0.54 CYP19A1 (0.77)
SCHEMBL9789477 0.54 CYP19A1 (0.77)
SCHEMBL9789472 0.54 CYP19A1 (0.77)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111533767-A Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol 卢海元 2020-08-14 CN claimed
EP-2781599-B1 NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN TAGCYX BIOTECHNOLOGIES (JP) 2019-05-08 EP claimed
US-9540650-B2 Nucleic acid fragment binding to target protein TAGCYX BIOTECHNOLOGIES (JP) 2017-01-10 US claimed
US-20150119254-A1 NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN TAGCYX BIOTECHNOLOGIES (JP) 2015-04-30 US claimed
EP-2781599-A1 NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN Riken (JP) 2014-09-24 EP claimed
US-8715984-B2 Modified tRNA containing unnatural base and use thereof RIKEN (JP) 2014-05-06 US claimed
EP-1970445-B1 METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS RIKEN (JP) 2012-09-26 EP claimed
US-8030478-B2 Method for nucleic acid replication and novel artificial base pairs RIKEN (JP) 2011-10-04 US claimed
US-20100323364-A1 MODIFIED tRNA CONTAINING UNNATURAL BASE AND USE THEREOF THE UNIVERSITY OF TOKYO (JP) 2010-12-23 US claimed
EP-2246428-A1 MODIFIED TRNA CONTAINING NON-NATURAL NUCLEOTIDE AND USE THEREOF The University of Tokyo (JP) 2010-11-03 EP claimed
US-20100036111-A1 METHOD FOR REPLICATING NUCLEIC ACIDS AND NOVEL UNNATURAL BASE PAIRS RIKEN (JP) 2010-02-11 US claimed
EP-1970445-A1 METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS Riken (JP) 2008-09-17 EP claimed
CN-108350459-B Cancer cell-binding DNA aptamers 新加坡科技研究局 2022-05-27 CN disclosed
EP-3369820-B1 DNA APTAMER CAPABLE OF BONDING TO VWF TAGCYX BIOTECHNOLOGIES INC (JP) 2021-12-08 EP disclosed
CN-108350461-B vWF-binding DNA aptamers 塔古西库斯生物株式会社 2021-10-19 CN disclosed
EP-3369819-B1 DNA APTAMER BINDING TO CANCER CELL AGENCY SCIENCE TECH & RES (SG) 2020-11-18 EP disclosed
EP-2246428-A1 MODIFIED TRNA CONTAINING NON-NATURAL NUCLEOTIDE AND USE THEREOF The University of Tokyo (JP) 2010-11-03 EP disclosed
US-20100036111-A1 METHOD FOR REPLICATING NUCLEIC ACIDS AND NOVEL UNNATURAL BASE PAIRS RIKEN (JP) 2010-02-11 US disclosed
WO-2009123216-A1 NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY 独立行政法人理化学研究所 (JP) 2009-10-08 WO disclosed
EP-1970445-A1 METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS Riken (JP) 2008-09-17 EP disclosed