Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20375645 | 0.86 | GPR119 (0.55) | GPR119PIK3CD | |
| SCHEMBL12236463 | 0.85 | GPR119 (0.59) | GPR119PIK3CD | |
| SCHEMBL12236445 | 0.84 | GPR119 (0.66) | GPR119PIK3CD | |
| SCHEMBL12259053 | 0.84 | GPR119 (0.55) | GPR119PIK3CD | |
| SCHEMBL1065920 | 0.84 | GPR119 (0.55) | GPR119PIK3CD | |
| SCHEMBL12236405 | 0.83 | GPR119 (0.62) | GPR119PIK3CD | |
| SCHEMBL12236496 | 0.80 | PIK3CD (0.52) | GPR119PIK3CD | |
| SCHEMBL20375465 | 0.79 | GPR119 (0.53) | GPR119PIK3CD | |
| SCHEMBL15260454 | 0.79 | GPR119 (0.74) | GPR119PIK3CD | |
| SCHEMBL20375411 | 0.78 | GPR119 (0.58) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382204-B1 | PYRIMIDINE DERIVATIVES AS GPCR MODULATORS FOR USE IN THE TREATMENT OF OBESITY AND DIABETES | MERCK SHARP & DOHME (US) | 2018-07-11 | — | — | EP | disclosed |