SCHEMBL20375464

SCHEMBL20375464

Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C2CC3CCC2C3)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
KCNQ3 O43525 1/20 0.31
KCNQ2 O43526 1/20 0.31
KCNQ4 P56696 1/20 0.31
KCNQ5 Q9NR82 1/20 0.31
JAK2 O60674 2/20 0.30
JAK1 P23458 2/20 0.30
TYK2 P29597 2/20 0.30
JAK3 P52333 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20358070 1.00 MEN1 (0.38) MEN1POLBGAAKMT2AKCNQ3
SCHEMBL27255189 0.81 MEN1 (0.44) MEN1POLBGAAKMT2A
SCHEMBL20358086 0.73 HIF1A (0.40)
SCHEMBL21085331 0.72 MEN1 (0.46) MEN1POLBGAAKMT2AKCNQ3
SCHEMBL20358182 0.71 MEN1 (0.45) MEN1POLBGAAKMT2AKCNQ3
SCHEMBL20375427 0.71 MEN1 (0.45) MEN1POLBGAAKMT2AKCNQ3
SCHEMBL24337701 0.71
SCHEMBL11910688 0.71 LPL (0.45)
SCHEMBL4020523 0.71 LPL (0.45)
SCHEMBL30573087 0.69 JAK2 (0.33) MEN1POLBGAAKMT2AJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201298-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-12-14 US disclosed
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 US disclosed
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP MEN1 4543/4885POLB 934/4885GAA 3502/4885
US-11201298-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP MEN1 4543/4885POLB 934/4885GAA 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.