⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12151300 | 0.73 | — | — | |
| SCHEMBL24801685 | 0.71 | — | — | |
| SCHEMBL16168829 | 0.71 | — | — | |
| SCHEMBL9966142 | 0.71 | — | — | |
| SCHEMBL18387208 | 0.68 | — | — | |
| SCHEMBL14984921 | 0.68 | — | — | |
| SCHEMBL8525312 | 0.67 | — | — | |
| SCHEMBL11932066 | 0.67 | — | — | |
| SCHEMBL17987716 | 0.67 | ALDH1A1 (0.37) | — | |
| SCHEMBL15261380 | 0.66 | SMYD3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973810-B2 | Methods for the treatment of neurological disorders | YUMANITY THERAPEUTICS, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20180193325-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2018-07-12 | — | — | US | disclosed |