Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2037585

C[C@H](N)C(=O)Oc1ccccc1.N

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.51
ATM Q13315 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
SLC1A3 P43003 1/20 0.45
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP1A2 P05177 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ANPEP P15144 1/20 0.40
LAP3 P28838 1/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9613925 1.00 ELANE (0.51) ELANEATML3MBTL1SLC1A3ALDH1A1
SCHEMBL133568 0.98 ELANE (0.53) ELANEATML3MBTL1SLC1A3ALDH1A1
SCHEMBL9939655 0.98 ELANE (0.53) ELANEATML3MBTL1SLC1A3ALDH1A1
SCHEMBL285949 0.98 ELANE (0.53) ELANEATML3MBTL1SLC1A3ALDH1A1
Hydrochloric Acid SCHEMBL10445713 0.96 ELANE (0.51) ELANEATML3MBTL1SLC1A3ALDH1A1
SCHEMBL28281300 0.96 ELANE (0.51) ELANEATML3MBTL1SLC1A3ALDH1A1
SCHEMBL28299146 0.96 ELANE (0.51) ELANEATML3MBTL1SLC1A3ALDH1A1
SCHEMBL28176721 0.96 ELANE (0.51) ELANEATML3MBTL1SLC1A3ALDH1A1
Hydrochloric Acid SCHEMBL19834657 0.96 ELANE (0.51) ELANEATML3MBTL1SLC1A3ALDH1A1
Malonic Acid SCHEMBL9222807 0.89 ELANE (0.46) ELANEATML3MBTL1SLC1A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011078667-A2 METHOD OF FINDING A BIOCATALYST HAVING AMMONIA LYASE ACTIVITY DSM IP ASSETS B.V. (NL) 2011-06-30 WO disclosed
CN-100387126-C Method of increasing content of flavonoids and phenolic substances in plants BASF AG (DE) 2008-05-14 CN disclosed
CN-1355672-A Method of increasing content of flavonoids and phenolic substances in plants BASF AG (DE) 2002-06-26 CN disclosed
CN-1177279-A Aromatic aldehydes as pesticides and their use for killing arachnids PROGUARD INC (US) 1998-03-25 CN disclosed