Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821528 | 1.00 | MEN1 (0.33) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL820934 | 0.91 | MAPT (0.34) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL820933 | 0.91 | MAPT (0.34) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL821610 | 0.88 | MAPT (0.36) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL821611 | 0.88 | MAPT (0.36) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL821530 | 0.88 | MEN1 (0.38) | MEN1KMT2AMAPTNPC1CYP1A2 | |
| SCHEMBL821531 | 0.88 | MEN1 (0.38) | MEN1KMT2AMAPTNPC1CYP1A2 | |
| SCHEMBL821710 | 0.84 | RIPK1 (0.35) | MEN1KMT2AMAPTNPC1CYP1A2 | |
| SCHEMBL20377114 | 0.84 | RIPK1 (0.35) | MEN1KMT2AMAPTNPC1CYP1A2 | |
| SCHEMBL821718 | 0.84 | MEN1 (0.35) | MEN1KMT2AMAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | claimed |