Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2037899

CC(P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1.[Cl-].[Cl-].[Pd+2]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 2/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
ACHE known ✓ P22303 1/20 0.30
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.41
ESR1 P03372 4/20 0.34
ESR2 Q92731 4/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
TRPA1 O75762 2/20 0.31
TAAR1 Q96RJ0 4/20 0.31
MAOA P21397 1/20 0.31
SLC6A4 P31645 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP2A6 P11509 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1535292 0.95 TDP1 (0.41) TDP1CYP3A4ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL1258765 0.95 TDP1 (0.41) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL104024 0.95 TDP1 (0.45) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL3323494 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL1534405 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2TRPA1
SCHEMBL9764627 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL8106508 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2TRPA1
SCHEMBL9803953 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL10605346 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL9764212 0.92 TDP1 (0.43) TDP1CYP3A4ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139688-B2 Copolymers of 3,4-dialkoxythiophenes and methods for making and devices SOLVAY USA, INC. (US) 2015-09-22 US disclosed
US-20130023621-A1 COPOLYMERS OF 3,4-DIALKOXYTHIOPHENES AND METHODS FOR MAKING AND DEVICES PLEXTRONICS INC. 2013-01-24 US disclosed
EP-2513187-A2 COPOLYMERS OF 3,4-DIALKOXYTHIOPHENES AND METHODS FOR MAKING AND DEVICES Plextronics, Inc. (US) 2012-10-24 EP disclosed
WO-2011075644-A2 COPOLYMERS OF 3,4-DIALKOXYTHIOPHENES AND METHODS FOR MAKING AND DEVICES PLEXTRONICS, INC. (US) 2011-06-23 WO disclosed
EP-0988331-B1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS PROMERUS LLC (US) 2004-09-01 EP disclosed
US-6265506-B1 AMORPHOUS COPOLYMERS THE B. F. GOODRICH COMPANY 2001-07-24 US disclosed
EP-0988331-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS THE B.F. GOODRICH COMPANY (US) 2000-03-29 EP disclosed
WO-1998056839-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS THE B.F. GOODRICH COMPANY (US) 1998-12-17 WO disclosed