SCHEMBL20384010

SCHEMBL20384010

C[Si](C)(CCCC(=O)O)O[Si](C)(C)O[Si](C)(C)CCCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
LMNA P02545 2/20 0.42
SLC22A6 Q4U2R8 2/20 0.42
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
AKR1B1 P15121 1/20 0.39
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 6/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38
HDAC11 Q96DB2 5/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13038564 0.94 TSHR (0.41) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL19999974 0.92 AKR1B1 (0.48) TSHRLMNASLC22A6AKR1B1ALDH1A1
SCHEMBL23860276 0.92 TSHR (0.48) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL512941 0.91 TSHR (0.48) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL20384009 0.91 TSHR (0.47) TSHRLMNASLC22A6NFKB1PMP22
Hydrochloric Acid SCHEMBL7534254 0.89 TSHR (0.46) TSHRLMNASLC22A6NFKB1PMP22
Hydrochloric Acid SCHEMBL5368847 0.89 TSHR (0.46) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL13042886 0.88 LMNA (0.41) TSHRLMNASLC22A6NFKB1PMP22
Azelaic Acid SCHEMBL8198302 0.87 TSHR (0.52) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL19700255 0.87 TSHR (0.43) TSHRLMNASLC22A6NFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735957-A Preparation method of self-lubricating silica gel and application of self-lubricating silica gel in shower head 广州市瑞合新材料科技有限公司 2025-04-01 CN disclosed
US-20250002690-A1 POLYCARBONATE COMPOSITION COMPRISING A SURFACE-TREATED CALCIUM CARBONATE-CONTAINING MATERIAL OMYA INTERNATIONAL AG (CH) 2025-01-02 US disclosed
CN-118843217-A High-temperature-resistant heating wire and preparation method and application thereof 云南钜盛电器科技有限公司 2024-10-25 CN disclosed
EP-4430118-A1 POLYCARBONATE COMPOSITION COMPRISING A SURFACE-TREATED CALCIUM CARBONATE-CONTAINING MATERIAL Omya International AG (CH) 2024-09-18 EP disclosed
CN-118251451-A Polycarbonate composition comprising surface-treated calcium carbonate-containing material OMYA国际股份公司 2024-06-25 CN disclosed
CN-117619692-A Artificial stone surface skin-feel scratch-resistant and stain-resistant coating, and preparation method and product thereof 九牧厨卫股份有限公司 2024-03-01 CN disclosed
WO-2023079166-A1 POLYCARBONATE COMPOSITION COMPRISING A SURFACE-TREATED CALCIUM CARBONATE-CONTAINING MATERIAL OMYA INTERNATIONAL AG (CH) 2023-05-11 WO disclosed
US-20180201795-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2018-07-19 US disclosed