Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385088 | 0.83 | HTT (0.46) | KMT2ASMN1; SMN2TSHRRAB9AALDH1A1 | |
| SCHEMBL20385112 | 0.80 | GAA (0.46) | KMT2AMETAP2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL20385093 | 0.80 | HDAC1 (0.41) | KMT2AHSD17B10RAB9AGRIN2DGRIN3B | |
| SCHEMBL20385132 | 0.80 | HPGD (0.48) | KMT2AMETAP2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL20385119 | 0.79 | CYP1A2 (0.47) | KMT2ARAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20385092 | 0.79 | HTT (0.41) | KMT2ASMN1; SMN2RAB9AGRIN2DGRIN3B | |
| SCHEMBL20385124 | 0.77 | GRIN2D (0.53) | KMT2AMETAP2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL30758630 | 0.77 | KMT2A (0.72) | KMT2AMETAP2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL2949130 | 0.77 | KMT2A (0.72) | KMT2AMETAP2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL20385139 | 0.75 | HDAC1 (0.42) | KMT2AMETAP2TSHRHSD17B10GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |