Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385147 | 0.89 | HPGD (0.48) | ALDH1A1TDP1TSHRKMT2AGAA | |
| SCHEMBL20385140 | 0.87 | HDAC1 (0.43) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20385171 | 0.86 | CLCN2 (0.43) | ALDH1A1CTSDCLCN2TSHRKMT2A | |
| SCHEMBL20385132 | 0.84 | HPGD (0.48) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL20385165 | 0.83 | HPGD (0.42) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20385116 | 0.78 | GRIN2D (0.47) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL20385125 | 0.76 | HPGD (0.50) | ALDH1A1TDP1TSHRKMT2AGAA | |
| SCHEMBL20385111 | 0.75 | KMT2A (0.48) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL20385150 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRKMT2AGAA | |
| SCHEMBL20385159 | 0.74 | KCNN4 (0.45) | ALDH1A1KMT2AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |