Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385125 | 0.90 | HPGD (0.50) | HPGDALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL20385116 | 0.89 | GRIN2D (0.47) | HPGDALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL20385132 | 0.88 | HPGD (0.48) | HPGDALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL20385152 | 0.85 | HTT (0.47) | ALDH1A1MAPTTSHRSMN1; SMN2RAB9A | |
| SCHEMBL20385140 | 0.83 | HDAC1 (0.43) | HPGDALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL20385166 | 0.81 | HPGD (0.44) | HPGDALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL20385113 | 0.80 | TSHR (0.51) | HPGDALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL20385162 | 0.80 | KCNN4 (0.40) | HPGDALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL20385173 | 0.80 | NPC1 (0.47) | HPGDALDH1A1TSHRSMN1; SMN2RAB9A | |
| SCHEMBL20385146 | 0.79 | KMT2A (0.40) | HPGDALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |