Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385116 | 0.89 | GRIN2D (0.47) | HPGDKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20385165 | 0.88 | HPGD (0.42) | HPGDCASP1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL20385094 | 0.84 | HDAC1 (0.46) | KMT2AHTTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL20385125 | 0.84 | HPGD (0.50) | HPGDKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20385140 | 0.83 | HDAC1 (0.43) | HPGDKMT2AHTTALDH1A1GAA | |
| SCHEMBL20385113 | 0.82 | TSHR (0.51) | HPGDKMT2AALDH1A1GAAMAPT | |
| SCHEMBL20385129 | 0.81 | HPGD (0.50) | HPGDKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20385173 | 0.81 | NPC1 (0.47) | HPGDKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20385164 | 0.80 | HTT (0.48) | HPGDCASP1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL20385146 | 0.76 | KMT2A (0.40) | HPGDKMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |