Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457137 | 0.74 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL2756682 | 0.70 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL13071128 | 0.70 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL14665614 | 0.69 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL14665681 | 0.69 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL13041695 | 0.69 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL15747134 | 0.69 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL30572488 | 0.69 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL9980119 | 0.69 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL30572573 | 0.67 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130227-A1 | AROMATIC RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 山东罗欣药业集团股份有限公司 | 2018-07-19 | — | — | WO | disclosed |