Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 11/20 | 0.62 |
| ▸ | LIG1 | P18858 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25773001 | 0.92 | PCNA (0.72) | PCNALIG1THRBTHRATAAR1 | |
| SCHEMBL22382798 | 0.87 | PCNA (0.83) | PCNALIG1THRBTHRA | |
| SCHEMBL20385967 | 0.86 | THRB (0.54) | PCNALIG1THRBTHRATAAR1 | |
| SCHEMBL19048382 | 0.85 | PCNA (0.84) | PCNALIG1THRBTHRA | |
| SCHEMBL4449390 | 0.79 | PCNA (0.74) | PCNALIG1THRBTHRA | |
| SCHEMBL16124413 | 0.78 | PCNA (0.78) | PCNALIG1THRBTHRA | |
| SCHEMBL25773004 | 0.78 | TAAR1 (0.64) | PCNALIG1TAAR1SLC6A2 | |
| SCHEMBL16124414 | 0.78 | PCNA (0.78) | PCNALIG1THRBTHRA | |
| SCHEMBL12726457 | 0.78 | THRB (0.70) | PCNALIG1THRBTHRA | |
| SCHEMBL25772999 | 0.78 | THRB (0.70) | PCNALIG1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126324-B1 | A PROCESS FOR PREPARATION OF LEVOTHYROXINE AND SALTS THEREOF | LUPIN LTD (IN) | 2018-07-18 | — | — | EP | disclosed |