Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 10/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365718 | 0.86 | QPCT (0.63) | QPCTPOLBABL1KDRL3MBTL1 | |
| SCHEMBL14396880 | 0.85 | QPCT (0.59) | QPCTPOLBABL1KDRL3MBTL1 | |
| SCHEMBL21565623 | 0.85 | QPCT (0.56) | QPCTPOLBABL1KDRHTT | |
| SCHEMBL19806109 | 0.79 | QPCT (0.50) | QPCTPOLBABL1KDRL3MBTL1 | |
| SCHEMBL12858794 | 0.77 | MAPT (0.49) | QPCTPOLBKDM4EALDH1A1MAPT | |
| SCHEMBL29902860 | 0.77 | NAMPT (0.56) | QPCTPOLBABL1L3MBTL1HTT | |
| SCHEMBL29902873 | 0.77 | NAMPT (0.56) | QPCTPOLBABL1L3MBTL1HTT | |
| SCHEMBL30265304 | 0.76 | HTT (0.73) | POLBL3MBTL1HTTHDAC6MAPK1 | |
| SCHEMBL12633973 | 0.76 | QPCT (0.47) | QPCTPOLBL3MBTL1HTT | |
| SCHEMBL5151137 | 0.75 | NAMPT (0.55) | QPCTPOLBL3MBTL1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3568133-B1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH ZUERICH (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2019179890-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH ZURICH (CH) | 2019-09-26 | — | — | WO | disclosed |
| EP-3543231-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018130537-A1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH Zürich (CH) | 2018-07-19 | — | — | WO | disclosed |