Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 4/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29902860 | 1.00 | NAMPT (0.56) | NAMPTCCNE1CDK2CDK5HDAC6 | |
| SCHEMBL5151137 | 0.81 | NAMPT (0.55) | NAMPTCCNE1CDK2CDK5HDAC6 | |
| SCHEMBL23675135 | 0.80 | NAMPT (0.50) | NAMPTCCNE1CDK2CDK5HDAC6 | |
| SCHEMBL14365718 | 0.80 | QPCT (0.63) | POLBQPCTL3MBTL1HTTABL1 | |
| SCHEMBL20385992 | 0.77 | QPCT (0.59) | HDAC6POLBQPCTL3MBTL1HTT | |
| SCHEMBL15558786 | 0.75 | CTNNB1 (0.68) | NAMPTCCNE1CDK2CDK5HDAC6 | |
| SCHEMBL30265139 | 0.75 | L3MBTL1 (0.65) | HDAC6POLBL3MBTL1HTTKMT2A | |
| SCHEMBL26686922 | 0.74 | PRKCI (0.53) | NAMPTHDAC6P2RY14POLBQPCT | |
| SCHEMBL7901545 | 0.74 | PRKCI (0.53) | NAMPTHDAC6POLBQPCTKDM4E | |
| SCHEMBL3154557 | 0.74 | P2RY14 (0.53) | NAMPTHDAC6P2RY14POLBQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077316-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Inc. (US) | 2022-10-26 | — | — | EP | disclosed |