Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472365 | 0.85 | TLR8 (0.45) | TLR8TLR7KCNH2 | |
| SCHEMBL20219389 | 0.84 | TLR8 (0.43) | TLR8TLR7KCNH2 | |
| SCHEMBL15469724 | 0.84 | TLR8 (0.43) | TLR8TLR7KCNH2 | |
| SCHEMBL20219653 | 0.79 | TLR8 (0.43) | TLR8TLR7KCNH2 | |
| SCHEMBL20386695 | 0.78 | TLR8 (0.42) | TLR8TLR7KCNH2 | |
| SCHEMBL15470290 | 0.78 | TLR8 (0.42) | TLR8TLR7KCNH2 | |
| SCHEMBL13195042 | 0.77 | KCNH2 (0.46) | TLR8TLR7KCNH2 | |
| SCHEMBL20219748 | 0.77 | KCNH2 (0.46) | TLR8TLR7KCNH2 | |
| SCHEMBL23472246 | 0.76 | KCNH2 (0.36) | TLR8TLR7KCNH2 | |
| SCHEMBL23472430 | 0.75 | TLR8 (0.57) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694484-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-18 | — | — | EP | disclosed |