Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195729 | 0.83 | TLR7 (0.54) | TLR8TLR7KCNH2 | |
| SCHEMBL13195694 | 0.83 | TLR7 (0.54) | TLR8TLR7KCNH2 | |
| SCHEMBL20219473 | 0.83 | TLR7 (0.54) | TLR8TLR7KCNH2 | |
| SCHEMBL20386651 | 0.82 | KCNH2 (0.59) | TLR8TLR7KCNH2NUDT1 | |
| SCHEMBL12692509 | 0.79 | NUDT1 (0.53) | TLR8TLR7KCNH2NUDT1 | |
| SCHEMBL13195135 | 0.79 | TLR8 (0.50) | TLR8TLR7KCNH2 | |
| SCHEMBL15470158 | 0.79 | TLR7 (0.43) | TLR8TLR7KCNH2 | |
| SCHEMBL23472386 | 0.78 | TLR8 (0.51) | TLR8TLR7KCNH2 | |
| SCHEMBL23472261 | 0.78 | TLR8 (0.44) | TLR8TLR7KCNH2 | |
| SCHEMBL18109629 | 0.78 | TLR8 (0.69) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |