Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.67 |
| ▸ | FNTB | P49356 | 13/20 | 0.67 |
| ▸ | HRAS | P01112 | 1/20 | 0.67 |
| ▸ | KRAS | P01116 | 1/20 | 0.67 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15977117 | 0.84 | FNTA (0.77) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL16499911 | 0.81 | FNTA (1.00) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL94663 | 0.81 | FNTA (1.00) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL30498791 | 0.80 | FNTA (0.99) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL22050803 | 0.79 | FNTA (0.86) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL20387082 | 0.79 | FNTA (0.74) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL21574309 | 0.79 | FNTA (0.52) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL21877258 | 0.70 | FNTA (0.61) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL18041271 | 0.70 | FNTA (0.61) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL18041272 | 0.70 | FNTA (0.61) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483263-B1 | HETEROCYCLIC COMPOUNDS THAT ARE ERK INHIBITORS | MERCK SHARP & DOHME (US) | 2018-07-18 | — | — | EP | disclosed |