Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.52 |
| ▸ | FNTB | P49356 | 17/20 | 0.52 |
| ▸ | HRAS | P01112 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050804 | 0.80 | FNTA (0.69) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL20387085 | 0.79 | FNTA (0.67) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL15977117 | 0.71 | FNTA (0.77) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL16499911 | 0.69 | FNTA (1.00) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL94663 | 0.69 | FNTA (1.00) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL13428549 | 0.69 | FNTA (0.77) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL22050803 | 0.68 | FNTA (0.86) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL20387082 | 0.67 | FNTA (0.74) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL13524156 | 0.63 | FNTA (0.76) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL13428513 | 0.63 | FNTA (0.65) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2947098-B1 | COMBINATION OF ANTI-CTLA4 ANTIBODY WITH GEMCITABINE FOR THE SYNERGISTIC TREATMENT OF PROLIFERATIVE DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2019-11-20 | — | — | EP | disclosed |