SCHEMBL203871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2705773	0.86	TP53 (0.49)	HSD17B10LMNATARBP2POLBTP53
	SCHEMBL924162	0.85	HSD17B10 (0.54)	HSD17B10LMNATARBP2THRBPOLB
	SCHEMBL13179907	0.85	HSD17B10 (0.58)	HSD17B10LMNATARBP2THRBPOLB
	SCHEMBL5762006	0.83	HSD17B10 (0.56)	HSD17B10LMNATARBP2THRBPOLB
	SCHEMBL5540713	0.83	HSD17B10 (0.53)	HSD17B10LMNATARBP2THRBPOLB
	SCHEMBL4830153	0.83	HSD17B10 (0.53)	HSD17B10LMNATARBP2THRBPOLB
	SCHEMBL6776092	0.83	KDM4E (0.64)	LMNATARBP2TP53PPARAKDM4E
	SCHEMBL201829	0.81	TARBP2 (0.53)	HSD17B10LMNATARBP2POLBTP53
	SCHEMBL1436227	0.81	HSD17B10 (0.54)	HSD17B10LMNATARBP2THRBPOLB
	SCHEMBL5544253	0.81	HSD17B10 (0.51)	HSD17B10LMNATARBP2THRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.