Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16737919 | 0.93 | TSHR (0.39) | THRBTSHRALDH1A1LPAR3LPAR1 | |
| SCHEMBL3677974 | 0.93 | TSHR (0.42) | THRBTSHRALDH1A1LPAR3LPAR1 | |
| SCHEMBL176509 | 0.90 | TSHR (0.40) | THRBTSHRALDH1A1BTN3A1LPAR3 | |
| SCHEMBL6466015 | 0.84 | THRB (0.35) | THRBTSHR | |
| SCHEMBL27781350 | 0.84 | THRB (0.40) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28874078 | 0.83 | TSHR (0.41) | THRBTSHRALDH1A1LPAR3LPAR1 | |
| SCHEMBL2944692 | 0.82 | THRB (0.44) | THRBTSHRALDH1A1 | |
| SCHEMBL6851650 | 0.82 | TSHR (0.38) | THRBTSHRALDH1A1 | |
| SCHEMBL541439 | 0.82 | TSHR (0.42) | THRBTSHRALDH1A1LPAR3LPAR1 | |
| SCHEMBL28874092 | 0.81 | TSHR (0.46) | THRBTSHRLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862384-A2 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2021-08-11 | — | — | EP | claimed |
| WO-2015077081-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP (US) | 2015-05-28 | — | — | WO | claimed |
| CN-108463493-B | Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate | SIO2医药产品公司 | 2021-10-15 | — | — | CN | disclosed |
| EP-3862384-A2 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2015077081-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP (US) | 2015-05-28 | — | — | WO | disclosed |
| EP-2512416-A2 | COSMETIC TREATMENT METHOD INVOLVING A COMPOUND CAPABLE OF CONDENSING IN SITU | L'Oréal (FR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073279-A2 | COSMETIC TREATMENT METHOD INVOLVING A COMPOUND CAPABLE OF CONDENSING IN SITU | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |