Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20389432 | 0.87 | NAMPT (0.69) | NAMPT | |
| SCHEMBL20379805 | 0.84 | NAMPT (0.65) | NAMPT | |
| SCHEMBL20388976 | 0.84 | NAMPT (0.75) | NAMPT | |
| SCHEMBL20389440 | 0.84 | NAMPT (0.73) | NAMPT | |
| SCHEMBL20389174 | 0.84 | NAMPT (0.70) | NAMPT | |
| SCHEMBL20389047 | 0.83 | NAMPT (0.56) | NAMPT | |
| SCHEMBL20389118 | 0.82 | NAMPT (0.69) | NAMPT | |
| SCHEMBL20389187 | 0.82 | HTT (0.64) | NAMPT | |
| SCHEMBL20389130 | 0.81 | NAMPT (0.69) | NAMPT | |
| SCHEMBL20389015 | 0.81 | NAMPT (0.65) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018132372-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2018-07-19 | — | — | WO | disclosed |