Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 9/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12681451 | 1.00 | XIAP (0.43) | XIAPBIRC2CDK5CDK5R1CCNA2 | |
| SCHEMBL12681463 | 0.92 | XIAP (0.39) | XIAPBIRC2CDK5CDK5R1CCNA2 | |
| SCHEMBL12681482 | 0.89 | CDK5 (0.40) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL12681422 | 0.88 | AAK1 (0.47) | — | |
| SCHEMBL20390891 | 0.88 | AAK1 (0.47) | — | |
| SCHEMBL12681423 | 0.87 | HDAC2 (0.39) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL12681406 | 0.87 | SCN9A (0.39) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL12680085 | 0.87 | XIAP (0.41) | XIAPBIRC2CDK5CDK5R1CCNA2 | |
| SCHEMBL12681408 | 0.85 | GPR142 (0.37) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL13907113 | 0.85 | XIAP (0.40) | XIAPBIRC2CDK5CDK5R1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203435-B1 | 6, 11-BRIDGED BIARYL MACROLIDES | ENANTA PHARM INC (US) | 2018-07-18 | — | — | EP | disclosed |