SCHEMBL20394149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18661517	0.87	PDE10A (0.46)	PDE10AKMT2APPP1CALMNAALDH1A1
	SCHEMBL20394199	0.82	KDM4E (0.42)	PDE10AKMT2APPP1CAGABRA1GABRG2
	SCHEMBL20394296	0.81	KMT2A (0.40)	PDE10AKMT2APPP1CAGABRA1GABRG2
	SCHEMBL18661341	0.81	CYP3A4 (0.47)	KMT2AHPGDKDM4ELMNASLC22A12
	SCHEMBL20394444	0.80	KDM4E (0.38)	PDE10AGPBAR1KMT2APPP1CAGABRA1
	SCHEMBL20394501	0.80	PDE10A (0.51)	PDE10AGPBAR1
	SCHEMBL18661516	0.79	PDE10A (0.45)	PDE10AKMT2APPP1CALMNAALDH1A1
	SCHEMBL20394376	0.79	DRD1 (0.38)	PDE10AKMT2APPP1CAGABRA1GABRG2
	SCHEMBL20394173	0.78	SYK (0.40)	PDE10AGPBAR1KMT2APPP1CAL3MBTL1
	SCHEMBL18661511	0.78	GPBAR1 (0.41)	PDE10AGPBAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.