SCHEMBL20394199

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18661517	0.85	PDE10A (0.46)	ALDH1A1SMN1; SMN2L3MBTL1LMNAKMT2A
	SCHEMBL20394397	0.84	GPBAR1 (0.40)	NPC1RAB9ASMN1; SMN2TP53HPGD
	SCHEMBL20394444	0.82	KDM4E (0.38)	KDM4EMAPTALDH1A1HSD17B10HTT
	SCHEMBL20394149	0.82	PDE10A (0.40)	KDM4EMAPTALDH1A1SMN1; SMN2HSD17B10
	SCHEMBL18661341	0.81	CYP3A4 (0.47)	KDM4EALDH1A1HSD17B10TSHRHPGD
	SCHEMBL18661511	0.80	GPBAR1 (0.41)	L3MBTL1PDE10ACYP1A2CYP2C9CYP2C19
	SCHEMBL20394296	0.79	KMT2A (0.40)	KDM4EMAPTALDH1A1SMN1; SMN2HTT
	SCHEMBL20394376	0.79	DRD1 (0.38)	KDM4EMAPTALDH1A1HTTPTGS2
	SCHEMBL18661516	0.77	PDE10A (0.45)	ALDH1A1SMN1; SMN2L3MBTL1LMNAKMT2A
	SCHEMBL20406571	0.76	PDE10A (0.38)	KDM4EMAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.