SCHEMBL20394161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20394244	0.89	PDE10A (0.46)	PDE10AKDM4ECCNCCDK8CYP1A2
	SCHEMBL20394320	0.88	PDE10A (0.46)	PDE10AKDM4ECCNCCDK8L3MBTL1
	SCHEMBL20394485	0.87	PDE10A (0.52)	PDE10AKDM4ECCNCCDK8MAPT
	SCHEMBL18661529	0.86	PDE10A (0.60)	PDE10AALDH1A1CCNCCDK8POLB
	SCHEMBL20406628	0.84	PDE10A (0.57)	PDE10AKDM4EALDH1A1CCNCCDK8
	SCHEMBL20394192	0.83	MAPT (0.47)	PDE10AKDM4EL3MBTL1MAPTNPBWR1
	SCHEMBL25191466	0.77	ALDH1A1 (0.56)	PDE10AKDM4EALDH1A1CYP1A2L3MBTL1
	SCHEMBL30414735	0.77	ALDH1A1 (0.56)	PDE10AKDM4EALDH1A1CYP1A2L3MBTL1
	SCHEMBL11812647	0.76	TDP1 (0.50)	ALDH1A1CYP1A2L3MBTL1MAPTPOLB
	SCHEMBL2458300	0.76	PDE10A (0.53)	PDE10AALDH1A1CYP1A2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.