Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.55 |
| ▸ | HRH2 | P25021 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643103 | 0.92 | TPSAB1 (0.63) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| SCHEMBL12544270 | 0.92 | TPSAB1 (0.51) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL12544178 | 0.92 | TPSAB1 (0.62) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| SCHEMBL2039789 | 0.87 | TPSAB1 (0.54) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| SCHEMBL12642971 | 0.86 | TPSAB1 (0.68) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2041445 | 0.85 | TPSAB1 (0.67) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| SCHEMBL2036326 | 0.85 | TPSAB1 (0.52) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| SCHEMBL2033816 | 0.85 | TPSAB1 (0.64) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| SCHEMBL12542373 | 0.84 | TPSAB1 (0.53) | TPSAB1HRH2CNR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2033817 | 0.84 | TPSAB1 (0.63) | TPSAB1HRH2CNR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516419-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079102-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2011-06-30 | — | — | WO | disclosed |