SCHEMBL20394271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20406788	0.86	NPC1 (0.54)	MAPTKDM4EPDE10APDGFRBELANE
	SCHEMBL20394347	0.86	KDM4E (0.46)	MAPTKDM4EPDE10APDGFRBPDGFRA
	SCHEMBL20755033	0.82	CYP1A2 (0.53)	KDM4EPDE10APDGFRBPDGFRACYP1A2
	SCHEMBL20394473	0.81	PDE10A (0.42)	PDE10AELANECYP1A2CYP3A4CYP2D6
	SCHEMBL20394377	0.80	PDE10A (0.47)	PDE10AELANETDP1ALDH1A1LMNA
	SCHEMBL20394281	0.80	PDE10A (0.47)	PDE10AELANEMEN1KMT2ATDP1
	SCHEMBL20394225	0.79	HSD17B10 (0.46)	MAPTKDM4EPDE10ACYP1A2CYP3A4
	SCHEMBL20394226	0.79	PDE10A (0.47)	MAPTKDM4EPDE10AELANECYP1A2
	SCHEMBL20394304	0.79	GRM5 (0.47)	MAPTKDM4EPDE10AELANETDP1
	SCHEMBL20406721	0.78	PDE10A (0.44)	KDM4EPDE10AELANECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.