SCHEMBL20394347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20394225	0.92	HSD17B10 (0.46)	KDM4EMAPTPDE10ACYP1A2CYP3A4
	SCHEMBL20394239	0.92	MEN1 (0.44)	PDE10AMEN1KMT2APABPC1ACACB
	SCHEMBL20394497	0.91	PDE10A (0.50)	KDM4EMAPTPDE10AMEN1KMT2A
	SCHEMBL20394316	0.89	CYP11B1 (0.47)	KDM4EMAPTPDE10AELANELTA4H
	SCHEMBL20406788	0.87	NPC1 (0.54)	KDM4EMAPTPDE10AMEN1KMT2A
	SCHEMBL20394271	0.86	MAPT (0.45)	KDM4EMAPTPDE10AMEN1KMT2A
	SCHEMBL20406447	0.84	ACACB (0.46)	MEN1KMT2APABPC1ACACBACACA
	SCHEMBL20406193	0.82	PDE10A (0.43)	PDE10ARAB9AELANE
	SCHEMBL20394304	0.81	GRM5 (0.47)	KDM4EMAPTPDE10AELANE
	SCHEMBL20394359	0.81	PDE10A (0.45)	PDE10AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.