Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31414709 | 1.00 | POLB (0.41) | POLBTDP1NQO2CYP1A2KMT2A | |
| SCHEMBL2144116 | 0.84 | S1PR4 (0.43) | NQO2ALDH1A1KDM4ENQO1S1PR4 | |
| SCHEMBL29769759 | 0.84 | S1PR4 (0.43) | NQO2ALDH1A1KDM4ENQO1S1PR4 | |
| SCHEMBL10112833 | 0.81 | ERN1 (0.38) | POLBTDP1NQO2KMT2AALDH1A1 | |
| SCHEMBL31651912 | 0.81 | PDE4B (0.35) | NQO2CYP1A2KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL30207735 | 0.79 | CYP1A2 (0.41) | POLBTDP1NQO2CYP1A2KMT2A | |
| SCHEMBL22621616 | 0.79 | POLB (0.52) | POLBTDP1NQO2CYP1A2KMT2A | |
| SCHEMBL2969903 | 0.79 | CYP1A2 (0.41) | POLBTDP1NQO2CYP1A2KMT2A | |
| SCHEMBL3792156 | 0.77 | S1PR4 (0.47) | NQO2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL16043514 | 0.76 | S1PR4 (0.46) | NQO2KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637735-A1 | DIMETHOXYPHENYL HETEROAROMATIC ALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Therapeutics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250270173-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| EP-3351533-B1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |
| WO-2025085701-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| EP-4511029-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2024138032-A1 | DIMETHOXYPHENYL HETEROAROMATIC ALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ENTHEOGENIX BIOSCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024138032-A1 | DIMETHOXYPHENYL HETEROAROMATIC ALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ENTHEOGENIX BIOSCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023205116-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023205116-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| CN-108290838-B | Biaryl derivatives and drugs containing the same | 科研制药株式会社 | 2021-12-31 | — | — | CN | disclosed |
| US-10647675-B2 | Biaryl derivative and medicine containing same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2020-05-12 | — | — | US | disclosed |
| US-20190055199-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2019-02-21 | — | — | US | disclosed |
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |
| CN-108290838-A | Biaryl derivatives and drugs containing the same | 科研制药株式会社 | 2018-07-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647675-B2 | Biaryl derivative and medicine containing same | MAN2B1, CBR3, MANBA | POLB 1481/4885TDP1 4417/4885NQO2 497/4885 |
| US-20190055199-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | MAN2B1, CBR3, MANBA | POLB 1481/4885TDP1 4417/4885NQO2 497/4885 |
| US-20250270173-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GRIN2C, HTR1A, GRIA4 | POLB 4692/4885TDP1 1309/4885NQO2 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.