Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18659590 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL2301668 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL18187497 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL2700383 | 0.89 | ALDH1A1 (0.65) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL23849829 | 0.88 | ALDH1A1 (0.68) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL28003819 | 0.88 | ALDH1A1 (0.68) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL27834079 | 0.88 | ALDH1A1 (0.68) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL28004276 | 0.88 | ALDH1A1 (0.68) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL2701059 | 0.88 | ALDH1A1 (0.68) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA | |
| SCHEMBL2701443 | 0.88 | ALDH1A1 (0.68) | SMN1; SMN2PDK1ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047919-A | Monovinylarene and conjugated diene block copolymer composition, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-116836335-A | Functionalized solution polymerized styrene-butadiene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116003660-A | Linear poly-1, 3-pentadiene elastomer with high trans-1, 4-structure content and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-116003712-A | Star-shaped poly-1, 3-pentadiene elastomer with high trans-1, 4-structure content, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-114685739-A | Block polymerization composition and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-113429515-A | Preparation method of liquid hydrocarbon polymer with controllable viscosity | 浙江众立合成材料科技股份有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-107586362-B | Modified conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-107556416-B | Liquid polyisoprene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-107556415-B | Liquid poly-conjugated diene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-107722402-B | Toughening agent composition, ABS resin and preparation method thereof | 中国石油化工股份有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-107722402-A | A kind of toughening agent composition and ABS resin and preparation method thereof | 中国石油化工股份有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-107586362-A | Modified conjugated diene polymer and preparation method thereof and butadiene-styrene rubber | 中国石油化工股份有限公司 | 2018-01-16 | — | — | CN | claimed |
| CN-107556416-A | A kind of liquid polyisoprene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-107556415-A | A kind of liquid poly-conjugated-diolefin rubber and preparation method thereof | 中国石油化工股份有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-104098743-B | A kind of random butylbenzene copolymer of multi-arm star of wide distribution polyisocyanates coupling and preparation method thereof | 中国石油化工股份有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-104628952-A | Monovinylarene-conjugated diene copolymer, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-05-20 | — | — | CN | claimed |
| CN-102558465-B | Synthesizing method of solution polymerized styrene butadiene rubber | CHINA PETROLEUM & CHEMICAL | 2015-03-11 | — | — | CN | claimed |
| CN-104098743-A | Wide-distribution polyisocyanate-coupled multi-arm star random butadiene-styrene copolymer and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2014-10-15 | — | — | CN | claimed |
| CN-102558465-A | Synthesizing method of solution polymerized styrene butadiene rubber | CHINA PETROLEUM & CHEMICAL | 2012-07-11 | — | — | CN | claimed |
| CN-114057937-B | Conjugated diene polymer, preparation method and application thereof, and styrene-butadiene rubber | 中国石油化工股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118047919-A | Monovinylarene and conjugated diene block copolymer composition, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-118047997-A | Dynamically vulcanized thermoplastic elastomer material composition, application thereof and dynamically vulcanized thermoplastic elastomer material | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115785525-B | Structure regulator composition, liquid terpolymer, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117736375-A | Double-end functional solution polymerized styrene-butadiene rubber as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114057949-B | Conjugated diene polymer, preparation method and application thereof, and styrene-butadiene rubber | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117069881-A | Low cis-polybutadiene rubber and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117070005-A | Toughening agent composition, preparation method and application thereof, ABS resin and preparation method thereof | 中国石油化工股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116836335-A | Functionalized solution polymerized styrene-butadiene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113429515-B | Preparation method of viscosity-controllable liquid hydrocarbon polymer | 浙江众立合成材料科技股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116003712-A | Star-shaped poly-1, 3-pentadiene elastomer with high trans-1, 4-structure content, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-116003660-A | Linear poly-1, 3-pentadiene elastomer with high trans-1, 4-structure content and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115785525-A | Structure regulator composition, liquid terpolymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-111217940-B | Conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-111217941-B | Conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114685739-A | Block polymerization composition and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685900-A | Dynamic vulcanization thermoplastic elastomer composite material composition and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114057967-A | Method for preparing lithium polymer | 中国石油化工股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057949-A | Conjugated diene polymer, preparation method and application thereof, and styrene butadiene rubber | 中国石油化工股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057937-A | Conjugated diene polymer, preparation method and application thereof, and styrene butadiene rubber | 中国石油化工股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113929843-A | Styrene-piperylene-styrene block copolymer and synthetic method and application thereof | 中国石油化工股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-110372819-B | Conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-113429515-A | Preparation method of liquid hydrocarbon polymer with controllable viscosity | 浙江众立合成材料科技股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-109415447-B | Silane-mediated enhancement of rubber storage stability | 盛禧奥欧洲有限责任公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-109503747-B | Low cis-polybutadiene rubber and preparation method thereof, HIPS resin and preparation method thereof, and ABS resin | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-109251264-B | Low cis-polybutadiene rubber and preparation method thereof, and HIPS resin and preparation method thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-107586362-B | Modified conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-109503900-B | Toughening agent composition and preparation method thereof, and styrene resin and preparation method thereof | 中国石油化工股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-109251263-B | Low cis-polybutadiene rubber and preparation method thereof, and HIPS resin and preparation method thereof | 中国石油化工股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109251262-B | Low cis-polybutadiene rubber and preparation method thereof, and HIPS resin and preparation method thereof | 中国石油化工股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109503746-B | Low cis-polybutadiene rubber and preparation method thereof, HIPS resin and preparation method thereof, and ABS resin | 中国石油化工股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3351569-B1 | METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME | ETIC INC (JP) | 2020-11-04 | — | — | EP | disclosed |
| CN-107466307-B | Polymer blend for tires | 盛禧奥欧洲有限责任公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-107454907-B | Functionalized polymer blends for tires | 盛禧奥欧洲有限责任公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-107556415-B | Liquid poly-conjugated diene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-107556416-B | Liquid polyisoprene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-111217940-A | Conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-111217941-A | Conjugated diene polymer, preparation method thereof and styrene butadiene rubber | 中国石油化工股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-107722402-B | Toughening agent composition, ABS resin and preparation method thereof | 中国石油化工股份有限公司 | 2020-02-18 | — | — | CN | disclosed |
| CN-110372819-A | A kind of conjugated diene polymer and preparation method thereof and butadiene-styrene rubber | 中国石油化工股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| US-10428161-B2 | Method for producing modified solution-polymerized diene rubber to be blended with silica, and rubber composition containing same | ERIC Inc. (JP) | 2019-10-01 | — | — | US | disclosed |
| CN-106700159-B | Rubber composition and vulcanized rubber and its preparation method and application | 中国石油化工股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109503746-A | Low cis polybutadiene rubber and preparation method thereof and HIPS resin and preparation method thereof and ABS resin | 中国石油化工股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109503900-A | Toughening agent composition and preparation method thereof and styrene resin and preparation method thereof | 中国石油化工股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109503747-A | Low cis polybutadiene rubber and preparation method thereof and HIPS resin and preparation method thereof and ABS resin | 中国石油化工股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109415447-A | The rubber storage stability enhancing that silane mediates | 盛禧奥欧洲有限责任公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109251263-A | Low cis polybutadiene rubber and preparation method thereof and HIPS resin and preparation method thereof | 中国石油化工股份有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-109251264-A | Low cis polybutadiene rubber and preparation method thereof and HIPS resin and preparation method thereof | 中国石油化工股份有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-109251262-A | Low cis polybutadiene rubber and preparation method thereof and HIPS resin and preparation method thereof | 中国石油化工股份有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-106589247-B | Low cis polybutadiene rubber and its preparation method and application | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| US-20180273650-A1 | METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME | ETIC INC. (JP) | 2018-09-27 | — | — | US | disclosed |
| EP-3351569-A1 | METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME | Etic Inc. (JP) | 2018-07-25 | — | — | EP | disclosed |
| CN-107722402-A | A kind of toughening agent composition and ABS resin and preparation method thereof | 中国石油化工股份有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-104558455-B | A kind of butylbenzene copolymer and its preparation method and application | 中国石油化工股份有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-107586362-A | Modified conjugated diene polymer and preparation method thereof and butadiene-styrene rubber | 中国石油化工股份有限公司 | 2018-01-16 | — | — | CN | disclosed |
| CN-107556415-A | A kind of liquid poly-conjugated-diolefin rubber and preparation method thereof | 中国石油化工股份有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-107466307-A | Polymer blend for tires | 盛禧奥欧洲有限责任公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-107454907-A | Functionalized polymer blends for tires | 盛禧奥欧洲有限责任公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-104628952-B | Monovinylarene and conjugated diene copolymer and its preparation method and application | 中国石油化工股份有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-104558456-B | Block copolymer, block copolymer composition, vulcanized rubber, application of block copolymer, block copolymer composition and vulcanized rubber and block copolymer preparation method | 中国石油化工股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-105777946-A | Double-end modified star solution polymerized styrene-butadiene rubber and preparation method and vulcanized rubber and application thereof | 中国石油化工股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-103848938-B | A kind of terpolymer of selective hydration and its preparation method and application | 中国石油化工股份有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-105623177-A | Monovinylarene-conjugated dialkene copolymer composition and vulcanized rubber and application thereof | CHINA PETROLEUM & CHEM CORP | 2016-06-01 | — | — | CN | disclosed |
| CN-104628952-A | Monovinylarene-conjugated diene copolymer, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-05-20 | — | — | CN | disclosed |
| CN-104558455-A | Butylbenzene copolymer as well as preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| CN-104558456-A | Block copolymer, block copolymer composition, vulcanized rubber, application of block copolymer, block copolymer composition and vulcanized rubber and block copolymer preparation method | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| CN-102558465-B | Synthesizing method of solution polymerized styrene butadiene rubber | CHINA PETROLEUM & CHEMICAL | 2015-03-11 | — | — | CN | disclosed |
| CN-104098743-A | Wide-distribution polyisocyanate-coupled multi-arm star random butadiene-styrene copolymer and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2014-10-15 | — | — | CN | disclosed |
| CN-104059196-A | Structure adjusting agent for olefin anionic polymerization, ternary copolymerized rubber, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2014-09-24 | — | — | CN | disclosed |
| CN-103848938-A | Selectively hydrogenated terpolymer and preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2014-06-11 | — | — | CN | disclosed |
| CN-103848939-A | Synthetic method of solution-polymerized styrene-butadiene rubber | North blasting engineering co ltd | 2014-06-11 | — | — | CN | disclosed |
| CN-101962423-B | Method for preparing ternarypolymerization rubber and application thereof | CHINA PETROLEUM & CHEMICAL | 2012-11-28 | — | — | CN | disclosed |
| CN-102558465-A | Synthesizing method of solution polymerized styrene butadiene rubber | CHINA PETROLEUM & CHEMICAL | 2012-07-11 | — | — | CN | disclosed |
| CN-101962423-A | Method for preparing ternarypolymerization rubber and application thereof | CHINA PETROLEUM & CHEMICAL | 2011-02-02 | — | — | CN | disclosed |
| CN-101316730-B | Silane-sulfide chain end modified elastomeric polymers | DOW GLOBAL TECHNOLOGIES INC | 2010-11-10 | — | — | CN | disclosed |
| CN-101316730-A | Silane-sulfide chain end modified elastomeric polymers | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-101316730-A | Silane-sulfide chain end modified elastomeric polymers | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-12-03 | — | — | CN | disclosed |