SCHEMBL20394649

SCHEMBL20394649

C=C[Si](OCCCC)(OCCCC)OCCCC.[SiH4]

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 2/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
ATM Q13315 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129087 0.98 TSHR (0.40) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL27787472 0.93 TSHR (0.38) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL931900 0.91 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL28994937 0.91 TSHR (0.39) TSHRHPGD
SCHEMBL929651 0.91 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL720929 0.91 TSHR (0.37) TSHRHPGDALDH1A1
SCHEMBL11737703 0.89 TSHR (0.41) TSHRHPGDALDH1A1CYP3A4
SCHEMBL11737742 0.89 TSHR (0.41) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL6511822 0.88 TSHR (0.41) TSHR
SCHEMBL131115 0.88 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351569-B1 METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME ETIC INC (JP) 2020-11-04 EP disclosed
US-10428161-B2 Method for producing modified solution-polymerized diene rubber to be blended with silica, and rubber composition containing same ERIC Inc. (JP) 2019-10-01 US disclosed
US-20180273650-A1 METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME ETIC INC. (JP) 2018-09-27 US disclosed
EP-3351569-A1 METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME Etic Inc. (JP) 2018-07-25 EP disclosed