SCHEMBL931900

SCHEMBL931900

C=C[Si](OCC)(OCCCC)OCCCC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 2/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL929651 1.00 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL129087 0.93 TSHR (0.40) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL17391539 0.92 TSHR (0.37) TSHR
SCHEMBL17391628 0.92 TSHR (0.37) TSHR
SCHEMBL20394649 0.91 TSHR (0.39) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL22654245 0.90 HPGD (0.33) TSHRHPGD
SCHEMBL27787472 0.89 TSHR (0.38) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL28994937 0.87 TSHR (0.39) TSHRHPGD
SCHEMBL931235 0.86
SCHEMBL720929 0.86 TSHR (0.37) TSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272878-B1 Coupled polymers and manufacturing method thereof TSRC CORP (TW) 2013-12-18 EP claimed
US-8481649-B2 Coupled polymers and manufacturing method thereof TSRC CORPORATION (TW) 2013-07-09 US claimed
US-20110009588-A1 COUPLED POLYMERS AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2011-01-13 US claimed
EP-2272878-A1 Coupled polymers and manufacturing method thereof TSRC Corporation (TW) 2011-01-12 EP claimed
US-9657039-B2 Production method for alkoxysilanes NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-05-23 US disclosed
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-01-07 US disclosed
EP-2272878-B1 Coupled polymers and manufacturing method thereof TSRC CORP (TW) 2013-12-18 EP disclosed
US-8481649-B2 Coupled polymers and manufacturing method thereof TSRC CORPORATION (TW) 2013-07-09 US disclosed
CN-102212196-B Coupled copolymer and method for producing the same TSRC CORP 2013-03-06 CN disclosed
US-20110009588-A1 COUPLED POLYMERS AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2011-01-13 US disclosed
EP-2272878-A1 Coupled polymers and manufacturing method thereof TSRC Corporation (TW) 2011-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES MSMO1, MGAM, MACO1 TSHR 2938/4885HPGD 3038/4885ALDH1A1 2386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.