Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341372 | 0.90 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2L3MBTL1 | |
| SCHEMBL3173765 | 0.89 | KMT2A (0.44) | KMT2AFABP5FABP7EPHX2L3MBTL1 | |
| SCHEMBL11964044 | 0.85 | KMT2A (0.48) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL25797253 | 0.84 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL11902048 | 0.83 | KMT2A (0.45) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL26632669 | 0.82 | KMT2A (0.44) | KMT2AFABP5FABP7EPHX2L3MBTL1 | |
| SCHEMBL15181329 | 0.81 | KMT2A (0.51) | KMT2AFABP5FABP7EPHX2L3MBTL1 | |
| SCHEMBL25657529 | 0.80 | KMT2A (0.39) | KMT2AFABP5FABP7EPHX2OPRD1 | |
| SCHEMBL524832 | 0.78 | FABP5 (0.44) | KMT2AFABP5FABP7EPHX2MAPT | |
| SCHEMBL6013918 | 0.78 | FABP5 (0.44) | KMT2AFABP5FABP7EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507245-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011069063-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |