Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.76 |
| ▸ | PPARG | P37231 | 8/20 | 0.76 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.76 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.76 |
| ▸ | RXRA | P19793 | 2/20 | 0.76 |
| ▸ | F7 | P08709 | 7/20 | 0.62 |
| ▸ | F3 | P13726 | 7/20 | 0.62 |
| ▸ | PPARD | Q03181 | 6/20 | 0.62 |
| ▸ | PPARA | Q07869 | 6/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19193490 | 1.00 | ALDH1A1 (0.76) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL31461009 | 1.00 | ALDH1A1 (0.76) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL3683367 | 1.00 | ALDH1A1 (0.76) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL1664949 | 0.93 | PPARG (0.64) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL586010 | 0.93 | PPARG (0.64) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL2441819 | 0.93 | PPARG (0.64) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL466118 | 0.91 | PPARG (0.61) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL17473895 | 0.91 | PPARG (0.61) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL466117 | 0.91 | PPARG (0.61) | ALDH1A1PPARGCYP19A1FFAR1MAPT | |
| SCHEMBL105841 | 0.90 | ALDH1A1 (0.63) | ALDH1A1PPARGCYP19A1FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207123-A1 | CERAMIDE DERIVATIVES AS ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207123-A1 | CERAMIDE DERIVATIVES AS ANTICANCER AGENTS | SGMS1, CERT1, CERS2 | ALDH1A1 2463/4885PPARG 3252/4885CYP19A1 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.