Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16896533 | 0.84 | RAB9A (0.54) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL16896535 | 0.82 | SMN1; SMN2 (0.54) | RAB9AALDH1A1KMT2ANPC1MAPT | |
| SCHEMBL29505379 | 0.82 | SMN1; SMN2 (0.54) | RAB9AALDH1A1KMT2ANPC1MAPT | |
| SCHEMBL16896310 | 0.75 | KMT2A (0.48) | RAB9AALDH1A1KMT2ALMNATDP1 | |
| SCHEMBL29505520 | 0.75 | KMT2A (0.48) | RAB9AALDH1A1KMT2ALMNATDP1 | |
| SCHEMBL6125241 | 0.75 | NPC1 (0.57) | RAB9AHTR3ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3468835 | 0.74 | NPC1 (0.56) | RAB9AHTR3ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL14046555 | 0.72 | NPC1 (0.74) | RAB9AALDH1A1HTR3ANPC1MAPT | |
| SCHEMBL20398193 | 0.71 | RAB9A (0.42) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL6125228 | 0.70 | RAB9A (0.70) | RAB9AALDH1A1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208605-A1 | Substituted Aza Compounds as IRAK-4 Inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208605-A1 | Substituted Aza Compounds as IRAK-4 Inhibitors | IRAK4, IRAK2, IRAK1 | RAB9A 2855/4885ALDH1A1 1373/4885HTR3B 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.