Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 1.00 |
| ▸ | FAAH | O00519 | 6/20 | 0.69 |
| ▸ | CNR1 | P21554 | 2/20 | 0.69 |
| ▸ | CNR2 | P34972 | 2/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20398906 | 1.00 | SLC6A5 (1.00) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL26624672 | 1.00 | SLC6A5 (1.00) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL15649990 | 1.00 | SLC6A5 (1.00) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL20398904 | 1.00 | SLC6A5 (1.00) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL28031795 | 0.99 | SLC6A5 (0.98) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL26624581 | 0.94 | SLC6A5 (0.89) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL17204083 | 0.93 | SLC6A5 (0.87) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL13279669 | 0.93 | SLC6A5 (0.87) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL4348859 | 0.93 | SLC6A5 (0.87) | SLC6A5FAAHCNR1CNR2EPHX2 | |
| SCHEMBL22034112 | 0.93 | SLC6A5 (0.87) | SLC6A5FAAHCNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018132876-A1 | NOVEL GLYCINE TRANSPORT INHIBITORS FOR THE TREATMENT OF PAIN | THE UNIVERSITY OF SYDNEY (AU) | 2018-07-26 | — | — | WO | disclosed |