Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18426164 | 0.91 | LTB4R2 (0.51) | LTB4R2LMNAKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL18425843 | 0.90 | LTB4R2 (0.39) | LTB4R2LMNAKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL20401293 | 0.89 | LTB4R2 (0.48) | LTB4R2LMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL18424860 | 0.88 | LMNA (0.43) | LTB4R2LMNAKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL20183889 | 0.86 | LTB4R2 (0.58) | LTB4R2LMNAMAPK1TSHRRAB9A | |
| SCHEMBL18425364 | 0.84 | LTB4R2 (0.60) | LTB4R2LMNAMAPK1RAB9A | |
| SCHEMBL20400018 | 0.84 | LTB4R2 (0.49) | LTB4R2LMNAKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL18425217 | 0.84 | LTB4R2 (0.47) | LTB4R2LMNAMAPK1RAB9A | |
| SCHEMBL22367976 | 0.82 | LTB4R2 (0.57) | LTB4R2LMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL20183893 | 0.82 | CNR2 (0.46) | LTB4R2LMNAKDM4EMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327000-B1 | NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT | UNIV DONGGUK IND ACAD COOP (KR) | 2020-09-02 | — | — | EP | claimed |
| WO-2018135918-A1 | PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BLT INHIBITING ACTIVITY AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 동국대학교 산학협력단 | 2018-07-26 | — | — | WO | disclosed |