Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 8/20 | 0.41 |
| ▸ | JAK3 | P52333 | 7/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24689072 | 1.00 | DPP4 (0.42) | DPP4DPP7TEAD1JAK3DPP8 | |
| SCHEMBL20849664 | 1.00 | DPP4 (0.42) | DPP4DPP7TEAD1JAK3DPP8 | |
| SCHEMBL22296413 | 0.90 | JAK3 (0.41) | DPP4DPP7JAK3 | |
| SCHEMBL17179524 | 0.90 | JAK3 (0.41) | DPP4DPP7JAK3 | |
| SCHEMBL17179528 | 0.90 | JAK3 (0.41) | DPP4DPP7JAK3 | |
| SCHEMBL29728768 | 0.87 | TEAD1 (0.43) | TEAD1JAK3TEAD3 | |
| SCHEMBL17833394 | 0.82 | JAK3 (0.40) | TEAD1JAK3 | |
| SCHEMBL17833391 | 0.82 | JAK3 (0.40) | TEAD1JAK3 | |
| SCHEMBL17833396 | 0.82 | JAK3 (0.40) | TEAD1JAK3 | |
| SCHEMBL20161816 | 0.81 | CYP1A2 (0.36) | TEAD1JAK3TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172940-A1 | METHODS FOR TREATING IMMUNE REFRACTORY LUNG CANCER | Revolution Medicines, Inc. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023133543-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2018136401-A1 | IMMUNOPROTEASOME INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2018-07-26 | — | — | WO | disclosed |