Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 8/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 5/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20849664 | 0.81 | DPP4 (0.42) | TEAD1JAK3TEAD3 | |
| SCHEMBL20399740 | 0.81 | DPP4 (0.42) | TEAD1JAK3TEAD3 | |
| SCHEMBL24689072 | 0.81 | DPP4 (0.42) | TEAD1JAK3TEAD3 | |
| SCHEMBL27089700 | 0.78 | TEAD1 (0.38) | TEAD1JAK3 | |
| SCHEMBL22296413 | 0.76 | JAK3 (0.41) | JAK3BTK | |
| SCHEMBL17179524 | 0.76 | JAK3 (0.41) | JAK3BTK | |
| SCHEMBL23735765 | 0.76 | TET3 (0.34) | TEAD1JAK3BTK | |
| SCHEMBL17179528 | 0.76 | JAK3 (0.41) | JAK3BTK | |
| SCHEMBL180337 | 0.76 | CYP1A2 (0.54) | CYP1A2TDP1 | |
| SCHEMBL16707763 | 0.73 | NCF1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |