SCHEMBL20400291

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20436401	0.87	ADORA2A (0.47)	ADORA2AADORA2BADORA1ROCK2PIM1
	SCHEMBL30401511	0.86	ADORA2A (0.49)	ADORA2AADORA2BADORA1
	SCHEMBL20400627	0.86	ADORA2A (0.49)	ADORA2AADORA2BADORA1
	SCHEMBL20416727	0.84	ADORA2A (0.54)	ADORA2AADORA2BADORA1ROCK2PIM1
	SCHEMBL20401259	0.84	ADORA2A (0.43)	ADORA2AADORA2BADORA1ROCK2PIM1
	SCHEMBL25432366	0.84	ADORA2A (0.41)	ADORA2AADORA2BADORA1ROCK2PIM1
	SCHEMBL30401458	0.83	ADORA2A (0.49)	ADORA2AADORA2BADORA1
	SCHEMBL20400817	0.83	ADORA2A (0.49)	ADORA2AADORA2BADORA1
	SCHEMBL24412404	0.83	ADORA2A (0.54)	ADORA2AADORA2BADORA1
	SCHEMBL20416586	0.82	ADORA2A (0.42)	ADORA2AADORA2BADORA1ROCK2PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.