SCHEMBL20400625

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20436404	0.91	ADORA2A (0.48)	ADORA2AADORA2BADORA1
	SCHEMBL20442127	0.89	TEK (0.47)	ADORA2AADORA2BADORA1CD74MIF
	SCHEMBL20417191	0.89	ADORA2A (0.46)	ADORA2AADORA2BADORA1CD74MIF
	SCHEMBL20416579	0.89	ADORA2A (0.48)	ADORA2AADORA2BADORA1
	SCHEMBL30401143	0.88	ADORA2A (0.46)	ADORA2AADORA2BADORA1TEKKDR
	SCHEMBL20401029	0.88	ADORA2A (0.46)	ADORA2AADORA2BADORA1TEKKDR
	SCHEMBL30401930	0.88	ADORA2A (0.46)	ADORA2AADORA2BADORA1CD74MIF
	SCHEMBL20401210	0.88	ADORA2A (0.46)	ADORA2AADORA2BADORA1CD74MIF
	SCHEMBL20401259	0.87	ADORA2A (0.43)	ADORA2AADORA2BADORA1GPR55TEK
	SCHEMBL20416781	0.87	KDR (0.46)	ADORA2AADORA2BADORA1TEKKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.