Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 18/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401366 | 0.86 | ADORA2A (0.53) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20400660 | 0.83 | ADORA2A (0.46) | ADORA2AADORA2BADORA1 | |
| SCHEMBL24915554 | 0.81 | ADORA2A (0.54) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20416537 | 0.81 | ADORA2B (0.44) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30400777 | 0.81 | ADORA2B (0.44) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20400688 | 0.78 | ADORA2A (0.73) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401243 | 0.76 | ADORA2A (0.39) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401236 | 0.76 | ADORA2A (0.62) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30401493 | 0.76 | ADORA2A (0.62) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401260 | 0.76 | ADORA2A (0.53) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136700-A1 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | ARCUS BIOSCIENCES, INC. (US) | 2018-07-26 | — | — | WO | disclosed |