Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 18/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30401167 | 0.83 | ADORA2A (0.53) | ADORA2AADORA2B | |
| SCHEMBL20416811 | 0.83 | ADORA2A (0.53) | ADORA2AADORA2B | |
| SCHEMBL20401473 | 0.80 | ADORA2A (0.60) | ADORA2AADORA2B | |
| SCHEMBL20401366 | 0.78 | ADORA2A (0.53) | ADORA2AADORA2B | |
| SCHEMBL23190410 | 0.78 | ADORA2A (0.47) | ADORA2AADORA2B | |
| SCHEMBL20400772 | 0.75 | ADORA2A (0.51) | ADORA2AADORA2B | |
| SCHEMBL20401483 | 0.73 | ADORA2A (0.47) | ADORA2AADORA2B | |
| SCHEMBL31440894 | 0.72 | ADORA2B (1.00) | ADORA2AADORA2B | |
| SCHEMBL31440983 | 0.72 | ADORA2A (1.00) | ADORA2AADORA2B | |
| SCHEMBL20436396 | 0.68 | ADORA2A (0.63) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136700-A1 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | ARCUS BIOSCIENCES, INC. (US) | 2018-07-26 | — | — | WO | disclosed |