Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447767 | 1.00 | QPCT (0.48) | QPCTQPCTLNPBWR1BRD4HTR2A | |
| SCHEMBL24996626 | 0.86 | QPCT (0.46) | QPCTQPCTLNPBWR1BRD4EGFR | |
| SCHEMBL30879444 | 0.86 | QPCT (0.46) | QPCTQPCTLNPBWR1BRD4EGFR | |
| SCHEMBL3379521 | 0.86 | EGFR (0.57) | QPCTQPCTLEGFRERBB2RECQL | |
| SCHEMBL3538945 | 0.84 | RECQL (0.51) | EGFRERBB2MCHR1GRIN1GRIN2B | |
| SCHEMBL10080163 | 0.84 | NPBWR1 (0.47) | QPCTQPCTLNPBWR1BRD4HTR2A | |
| SCHEMBL2443709 | 0.84 | NPBWR1 (0.47) | QPCTQPCTLNPBWR1BRD4HTR2A | |
| SCHEMBL24996628 | 0.84 | NPBWR1 (0.47) | QPCTQPCTLNPBWR1BRD4HTR2A | |
| SCHEMBL30879430 | 0.84 | NPBWR1 (0.47) | QPCTQPCTLNPBWR1BRD4HTR2A | |
| SCHEMBL530059 | 0.84 | IDO1 (0.47) | QPCTQPCTLNPBWR1BRD4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136935-A1 | 2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2018-07-26 | — | — | WO | disclosed |
| WO-2018136935-A1 | 2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2018-07-26 | — | — | WO | disclosed |