Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756337 | 0.94 | USP30 (0.32) | USP30CREBBP | |
| SCHEMBL20401805 | 0.89 | KMT2A (0.37) | USP30CREBBPHCRTR1HCRTR2KLKB1 | |
| SCHEMBL12016817 | 0.89 | USP30 (0.38) | USP30TP53 | |
| SCHEMBL2756253 | 0.89 | USP30 (0.38) | USP30TP53 | |
| SCHEMBL1985509 | 0.84 | USP30 (0.38) | USP30TP53 | |
| SCHEMBL1985511 | 0.84 | USP30 (0.38) | USP30TP53 | |
| SCHEMBL2756338 | 0.82 | KMT2A (0.36) | USP30CREBBPHCRTR1HCRTR2TP53 | |
| SCHEMBL1294080 | 0.80 | USP30 (0.36) | USP30TP53 | |
| SCHEMBL1294077 | 0.80 | USP30 (0.36) | USP30TP53 | |
| SCHEMBL12938495 | 0.78 | USP30 (0.41) | USP30TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285378-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-10039754-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-10028937-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028937-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | USP30 1963/4885CREBBP 597/4885HCRTR1 4113/4885 |
| US-20230285378-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | USP30 1963/4885CREBBP 597/4885HCRTR1 4113/4885 |
| US-10039754-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | USP30 1963/4885CREBBP 597/4885HCRTR1 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.