Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24834377 | 0.87 | MEN1 (0.55) | LIMK1TNKS2FEN1GSK3BJAK2 | |
| SCHEMBL23609820 | 0.87 | MEN1 (0.55) | LIMK1TNKS2CDK4CCND1TNKS | |
| SCHEMBL24833500 | 0.87 | MEN1 (0.55) | LIMK1TNKS2FEN1GSK3BJAK2 | |
| SCHEMBL22031877 | 0.85 | LIMK1 (0.55) | LIMK1TNKS2JAK2TNKSMAPT | |
| SCHEMBL24833378 | 0.84 | MEN1 (0.53) | LIMK1TNKS2FEN1GSK3BJAK2 | |
| SCHEMBL20402154 | 0.82 | GPR17 (0.42) | GSK3BGPR17PTGESTDO2CHEK1 | |
| SCHEMBL25442153 | 0.82 | LIMK1 (0.55) | LIMK1TNKS2JAK2TNKSMAPT | |
| SCHEMBL19109265 | 0.80 | LIMK1 (0.51) | LIMK1TNKS2TNKSMAPTRAB9A | |
| SCHEMBL15894714 | 0.79 | ALOX5 (0.46) | LIMK1TNKS2CDK4CCND1TNKS | |
| SCHEMBL24833490 | 0.79 | MEN1 (0.50) | TNKS2FEN1GSK3BCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | PAH, TYR, SLCO2A1 | LIMK1 1798/4885TNKS2 4087/4885FEN1 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.