Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 11/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20402217 | 0.85 | KDM4E (0.35) | ALDH1A1KDM4EGAAPSEN1PSEN2 | |
| SCHEMBL20402219 | 0.83 | KDM4E (0.34) | ALDH1A1KDM4EGAAPSEN1PSEN2 | |
| SCHEMBL20402196 | 0.83 | PSEN1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20402185 | 0.82 | PSEN1 (0.42) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20402149 | 0.82 | PSEN1 (0.42) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20402188 | 0.82 | PSEN1 (0.42) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20402207 | 0.80 | PSEN1 (0.41) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15024749 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAPSEN1PSEN2 | |
| SCHEMBL20402187 | 0.79 | PSEN1 (0.40) | ALDH1A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL9976726 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EGAAPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | PAH, TYR, SLCO2A1 | ALDH1A1 2073/4885KDM4E 1098/4885GAA 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.